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Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways

Intestinal stem cells (ISCs) in the Drosophila adult midgut are essential for maintaining tissue homeostasis and replenishing lost cells in response to tissue damage. Here we demonstrate that the Hippo (Hpo) signaling pathway, an evolutionarily conserved pathway implicated in organ size control and...

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Auteurs principaux: Ren, Fangfang, Wang, Bing, Yue, Tao, Yun, Eun-Young, Ip, Y. Tony, Jiang, Jin
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000252/
https://ncbi.nlm.nih.gov/pubmed/21078993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012759107
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