Neuroprotective Properties of Mildronate, a Small Molecule, in a Rat Model of Parkinson’s Disease

Previously, we have found that mildronate [3-(2,2,2-trimethylhydrazinium) propionate dihydrate], a small molecule with charged nitrogen and oxygen atoms, protects mitochondrial metabolism that is altered by inhibitors of complex I and has neuroprotective effects in an azidothymidine-neurotoxicity mo...

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Main Authors: Klusa, Vija Z., Isajevs, Sergejs, Svirina, Darja, Pupure, Jolanta, Beitnere, Ulrika, Rumaks, Juris, Svirskis, Simons, Jansone, Baiba, Dzirkale, Zane, Muceniece, Ruta, Kalvinsh, Ivars, Vinters, Harry V.
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000094/
https://ncbi.nlm.nih.gov/pubmed/21151450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11114465
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