Neuroprotective Properties of Mildronate, a Small Molecule, in a Rat Model of Parkinson’s Disease

Previously, we have found that mildronate [3-(2,2,2-trimethylhydrazinium) propionate dihydrate], a small molecule with charged nitrogen and oxygen atoms, protects mitochondrial metabolism that is altered by inhibitors of complex I and has neuroprotective effects in an azidothymidine-neurotoxicity mo...

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מידע ביבליוגרפי
Main Authors: Harry V. Vinters, Ruta Muceniece, Ivars Kalvinsh, Zane Dzirkale, Baiba Jansone, Simons Svirskis, Juris Rumaks, Sergejs Isajevs, Ulrika Beitnere, Jolanta Pupure, Darja Svirina, Vija Z. Klusa
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2010-11-01
סדרה:International Journal of Molecular Sciences
נושאים:
Parkinson’s disease
6-OHDA model
neuroimmunological biomarkers
mildronate
small molecule
גישה מקוונת:http://www.mdpi.com/1422-0067/11/11/4465/
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