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Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS

A method based on the coupling of high resolution size-exclusion liquid chromatography using a polymer stationary phase with inductively coupled plasma mass spectrometry was developed to study the interactions of two metallodrugs – cisplatin and RAPTA-T – with the serum proteins albumin and transfer...

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Detalhes bibliográficos
Main Authors: Groessl, Michael, Terenghi, Mattia, Casini, Angela, Elviri, Lisa, Lobinski, Ryszard, Dyson, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999900/
https://ncbi.nlm.nih.gov/pubmed/21151827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/B922701F
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