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Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verification
BACKGROUND: It is quite important to simulate the metabolic changes of a cell in response to the change in culture environment and/or specific gene knockouts particularly for the purpose of application in industry. If this could be done, the cell design can be made without conducting exhaustive expe...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999585/ https://ncbi.nlm.nih.gov/pubmed/21092096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-9-88 |
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