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Modeling and simulation of the main metabolism in Escherichia coli and its several single-gene knockout mutants with experimental verification

BACKGROUND: It is quite important to simulate the metabolic changes of a cell in response to the change in culture environment and/or specific gene knockouts particularly for the purpose of application in industry. If this could be done, the cell design can be made without conducting exhaustive expe...

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Detalhes bibliográficos
Main Authors: Kadir, Tuty Asmawaty Abdul, Mannan, Ahmad A, Kierzek, Andrzej M, McFadden, Johnjoe, Shimizu, Kazuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999585/
https://ncbi.nlm.nih.gov/pubmed/21092096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-9-88
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