Prolonged Survival of Allografts Induced by Mycobacterial Hsp70 Is Dependent on CD4+CD25+ Regulatory T Cells

BACKGROUND: Heat shock proteins (Hsps) are stress induced proteins with immunomodulatory properties. The Hsp70 of Mycobacterium tuberculosis (TBHsp70) has been shown to have an anti-inflammatory role on rodent autoimmune arthritis models, and the protective effects were demonstrated to be dependent...

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Hauptverfasser: Borges, Thiago J., Porto, Bárbara N., Teixeira, César A., Rodrigues, Marcelle, Machado, Felipe D., Ornaghi, Ana Paula, de Souza, Ana Paula D., Maito, Fabio, Pavanelli, Wander R., Silva, João S., Bonorino, Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999527/
https://ncbi.nlm.nih.gov/pubmed/21170379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014264
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