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Multistep carcinogenesis of perihilar cholangiocarcinoma arising in the intrahepatic large bile ducts

Flat-type “biliary intraepithelial neoplasia (BilIN)” and papillary-type “intraductal papillary neoplasm of the bile duct (IPN-B)” are proposed as precursors of invasive, perihilar intrahepatic cholangiocarcinoma (ICC). Three carcinogenetic pathways are proposed: BilIN progressing to tubular adenoca...

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Detalhes bibliográficos
Main Authors: Nakanuma, Yasuni, Sasaki, Motoko, Sato, Yasunori, Ren, Xiangshan, Ikeda, Hiroko, Harada, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999259/
https://ncbi.nlm.nih.gov/pubmed/21160963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v1.i1.35
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