Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease

The 8q24 locus, which contains the thyroglobulin (Tg) gene, was previously shown to be strongly linked with autoimmune thyroid disease (AITD). We sequenced all 48 exons of the Tg gene and identified 14 single-nucleotide polymorphisms (SNPs). Case control association studies demonstrated that an exon...

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I whakaputaina i:	Proc Natl Acad Sci U S A
Ngā kaituhi matua:	Ban, Yoshiyuki, Greenberg, David A., Concepcion, Erlinda, Skrabanek, Lucy, Villanueva, Ronald, Tomer, Yaron
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	National Academy of Sciences 2003
Ngā marau:	Biological Sciences
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2434175100
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