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A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor
Peptides bind MHC class I molecules by anchoring hydrophobic side chains into pockets in the peptide binding groove. Here, we report an immunogenic (in vitro and in vivo) MUC1 glycopeptide (MUC1–8-5GalNAc) bound to H-2K(b), fully crossreactive with the nonglycosylated variant. Molecular modeling sho...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2003
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299892/ https://ncbi.nlm.nih.gov/pubmed/14657390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2432220100 |
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