Pluronic-Modified Superoxide Dismutase 1 (SOD1) Attenuates Angiotensin II-Induced Increase in Intracellular Superoxide in Neurons

Overexpressing superoxide dismutase 1 (SOD1; also called Cu/ZnSOD), an intracellular superoxide (O2•−) scavenging enzyme, in central neurons inhibits angiotensin II (AngII) intra-neuronal signaling and normalizes cardiovascular dysfunction in diseases associated with enhanced AngII signaling in the...

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Hauptverfasser: Yi, Xiang, Zimmerman, Matthew C., Yang, Ruifang, Tong, Jing, Vinogradov, Serguei, Kabanov, Alexander V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998907/
https://ncbi.nlm.nih.gov/pubmed/20493251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.04.039
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