H(2)S Signals Through Protein S-Sulfhydration

Hydrogen sulfide (H(2)S), a messenger molecule generated by cystathionine γ-lyase, acts as a physiologic vasorelaxant. Mechanisms whereby H(2)S signals have been elusive. We now show that H(2)S physiologically modifies cysteines in a large number of proteins by S-sulfhydration. About 10 to 25% of ma...

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Detalhes bibliográficos
Main Authors: Mustafa, Asif K., Gadalla, Moataz M., Sen, Nilkantha, Kim, Seyun, Mu, Weitong, Gazi, Sadia K., Barrow, Roxanne K., Yang, Guangdong, Wang, Rui, Snyder, Solomon H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998899/
https://ncbi.nlm.nih.gov/pubmed/19903941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000464
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