Structural basis of peptide–carbohydrate mimicry in an antibody-combining site

The structure of a complex between the Fab fragment of the antibody (SYA/J6) specific for the cell surface O-antigen polysaccharide of the pathogen Shigella flexneri Y and an octapeptide (Met–Asp–Trp–Asn–Met–His–Ala–Ala), a functional mimic of the O-antigen, has been determined at 1.8-Å resolution....

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Bibliographic Details
Main Authors: Vyas, Nand K., Vyas, Meenakshi N., Chervenak, Mary C., Bundle, David R., Pinto, B. Mario, Quiocho, Florante A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC299889/
https://ncbi.nlm.nih.gov/pubmed/14645714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2431286100
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