HIV-1 Assembly: Viral Glycoproteins Segregate Quantally to Lipid Rafts that Associate Individually with HIV-1 Capsids and Virions

HIV-1 assembly depends on its structural protein, Gag, which after synthesis on ribosomes, traffics to the late endosome/plasma membrane, associates with HIV Env glycoprotein, and forms infectious virions. While Env and Gag migrate to lipid microdomains, their stoichiometry and specificity of intera...

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Main Authors: Leung, Kwanyee, Kim, Jae-Ouk, Ganesh, Lakshmanan, Kabat, Juraj, Schwartz, Owen, Nabel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Inc. 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998762/
https://ncbi.nlm.nih.gov/pubmed/18474355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.04.004
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