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Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells

Dendritic cells (DCs) capture and internalize human immunodeficiency virus (HIV)-1 through C-type lectins, including DC-SIGN. These cells mediate efficient infection of T cells by concentrating the delivery of virus through the infectious synapse, a process dependent on the cytoplasmic domain of DC-...

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Autors principals: Smith, Alvin L., Ganesh, Lakshmanan, Leung, Kwanyee, Jongstra-Bilen, Jenny, Jongstra, Jan, Nabel, Gary J.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118718/
https://ncbi.nlm.nih.gov/pubmed/17296787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061604
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