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Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene

Susceptibility to mouse plasmacytomagenesis is a complex genetic trait controlled by several Pctr loci (Pctr1, Pctr2, etc). Congenic strain analysis narrowed the genetic interval surrounding the Pctr2 locus, and genes identified in the interval were sequenced from susceptible BALB/c and resistant DB...

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Bibliografske podrobnosti
Main Authors: Bliskovsky, Valery, Ramsay, Edward S., Scott, John, DuBois, Wendy, Shi, Wei, Zhang, Shuling, Qian, Xiaolan, Lowy, Douglas R., Mock, Beverly A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC299869/
https://ncbi.nlm.nih.gov/pubmed/14634209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2431627100
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