Mitochondrial monoamine oxidase-A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery

BACKGROUND AND PURPOSE: We evaluated the role(s) of monoamine oxidase (MAO)-mediated H(2)O(2) generation on 5-hydroxytryptamine (5-HT)-induced tension development of isolated basilar artery of spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats. EXPERIMENTAL APPROACH: Basi...

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Hlavní autoři: Poon, Christina Chui Wa, Seto, Sai Wang, Au, Alice Lai Shan, Zhang, Qian, Li, Rachel Wai Sum, Lee, Wayne Yuk Wai, Leung, George Pak Heng, Kong, Siu Kai, Yeung, John Hok Keung, Ngai, Sai Ming, Ho, Ho Pui, Lee, Simon Ming Yuen, Chan, Shun Wan, Kwan, Yiu Wa
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998689/
https://ncbi.nlm.nih.gov/pubmed/20977458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00941.x
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