Mitochondrial monoamine oxidase-A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery

BACKGROUND AND PURPOSE: We evaluated the role(s) of monoamine oxidase (MAO)-mediated H(2)O(2) generation on 5-hydroxytryptamine (5-HT)-induced tension development of isolated basilar artery of spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats. EXPERIMENTAL APPROACH: Basi...

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Detalhes bibliográficos
Main Authors: Poon, Christina Chui Wa, Seto, Sai Wang, Au, Alice Lai Shan, Zhang, Qian, Li, Rachel Wai Sum, Lee, Wayne Yuk Wai, Leung, George Pak Heng, Kong, Siu Kai, Yeung, John Hok Keung, Ngai, Sai Ming, Ho, Ho Pui, Lee, Simon Ming Yuen, Chan, Shun Wan, Kwan, Yiu Wa
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998689/
https://ncbi.nlm.nih.gov/pubmed/20977458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00941.x
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