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The anti-aggregating effect of BAY 41-2272, a stimulator of soluble guanylyl cyclase, requires the presence of nitric oxide

BACKGROUND AND PURPOSE: The purpose of the present study was to determine whether a stimulator of soluble guanylyl cyclase, BAY 41-2272, inhibits platelet aggregation and to clarify its interaction with nitric oxide (NO). EXPERIMENTAL APPROACH: Blood was collected from anaesthetized Wistar Kyoto rat...

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Autors principals: Roger, Séverine, Badier-Commander, Cécile, Paysant, Jérôme, Cordi, Alex, Verbeuren, Tony J, Félétou, Michel
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998686/
https://ncbi.nlm.nih.gov/pubmed/20977455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00943.x
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