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Exploring the P-Glycoprotein Binding Cavity with Polyoxyethylene Alkyl Ethers
P-glycoprotein (ABCB1) moves allocrits from the cytosolic to the extracellular membrane leaflet, preventing their intrusion into the cytosol. It is generally accepted that allocrit binding from water to the cavity lined by the transmembrane domains occurs in two steps, a lipid-water partitioning ste...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998628/ https://ncbi.nlm.nih.gov/pubmed/21112283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.033 |
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