Calcium-Induced Folding and Stabilization of the Intrinsically Disordered RTX Domain of the CyaA Toxin

The adenylate cyclase toxin (CyaA) is one of the major virulence factors of Bordetella pertussis, the causative agent of whooping cough. Its C-terminal region, the receptor-binding domain (RD), contains ∼40 calcium-binding Repeat in ToXin (RTX) motifs, which are characteristic of many virulence fact...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chenal, Alexandre, Karst, Johanna C., Pérez, Ana Cristina Sotomayor, Wozniak, Anna Katarzyna, Baron, Bruno, England, Patrick, Ladant, Daniel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Biophysical Society 2010
Gaiak:
Protein
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998614/
https://ncbi.nlm.nih.gov/pubmed/21112299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.016
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