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Coupling between microtubule sliding, plus-end growth and spindle length revealed by kinesin-8 depletion

Mitotic spindle length control requires coordination between microtubule (MT) dynamics and motor-generated forces. To investigate how MT plus-end polymerization contributes to spindle length in Drosophila embryos, we studied the dynamics of the MT plus-end depolymerase, kinesin-8, and the effects of...

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Main Authors: Wang, Haifeng, Brust-Mascher, Ingrid, Cheerambathur, Dhanya, Scholey, Jonathan M.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998535/
https://ncbi.nlm.nih.gov/pubmed/20814910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20482
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