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Prediction of conformational changes by single mutation in the hepatitis B virus surface antigen (HBsAg) identified in HBsAg-negative blood donors

BACKGROUND: Selection of hepatitis B virus (HBV) by host immunity has been suggested to give rise to variants with amino acid substitutions at or around the 'a' determinant of the surface antigen (HBsAg), the main target of antibody neutralization and diagnostic assays. However, there have...

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Bibliografski detalji
Glavni autori: Ie, Susan I, Thedja, Meta D, Roni, Martono, Muljono, David H
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998485/
https://ncbi.nlm.nih.gov/pubmed/21087462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-326
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