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Prediction of conformational changes by single mutation in the hepatitis B virus surface antigen (HBsAg) identified in HBsAg-negative blood donors

BACKGROUND: Selection of hepatitis B virus (HBV) by host immunity has been suggested to give rise to variants with amino acid substitutions at or around the 'a' determinant of the surface antigen (HBsAg), the main target of antibody neutralization and diagnostic assays. However, there have...

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Detalhes bibliográficos
Main Authors: Ie, Susan I, Thedja, Meta D, Roni, Martono, Muljono, David H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998485/
https://ncbi.nlm.nih.gov/pubmed/21087462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-7-326
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