Intracellular Trafficking of Guanylate-Binding Proteins Is Regulated by Heterodimerization in a Hierarchical Manner

Guanylate-binding proteins (GBPs) belong to the dynamin family of large GTPases and represent the major IFN-γ-induced proteins. Here we systematically investigated the mechanisms regulating the subcellular localization of GBPs. Three GBPs (GBP-1, GBP-2 and GBP-5) carry a C-terminal CaaX-prenylation...

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Detalhes bibliográficos
Main Authors: Britzen-Laurent, Nathalie, Bauer, Michael, Berton, Valeria, Fischer, Nicole, Syguda, Adrian, Reipschläger, Simone, Naschberger, Elisabeth, Herrmann, Christian, Stürzl, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998424/
https://ncbi.nlm.nih.gov/pubmed/21151871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014246
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