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Peptidoglycan Recognition Proteins Protect Mice from Experimental Colitis by Promoting Normal Gut Flora and Preventing Induction of Interferon-γ

There are multiple mechanisms of maintaining tolerance in the gut that protect the intestine from excessive inflammatory response to intestinal microorganisms. We report here that all four mammalian Peptidoglycan Recognition Proteins (PGRPs or Pglyrps) protect the host from colitis induced by dextra...

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Detalhes bibliográficos
Main Authors: Saha, Sukumar, Jing, Xuefang, Park, Shin Yong, Wang, Shiyong, Li, Xinna, Gupta, Dipika, Dziarski, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998413/
https://ncbi.nlm.nih.gov/pubmed/20709292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.07.005
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