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PGLYRP-2 and Nod2 Are Both Required for Peptidoglycan-Induced Arthritis and Local Inflammation

Peptidoglycan recognition proteins (PGRPs) are structurally conserved from insects to mammals. Insect PGRPs have many host defense functions, whereas mammalian PGRPs only have bactericidal and amidase activities. We asked whether mammalian PGRPs have immunomodulating activities in peptidoglycan-indu...

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Detalhes bibliográficos
Main Authors: Saha, Sukumar, Qi, Jin, Wang, Shiyong, Wang, Minhui, Li, Xinna, Kim, Yun-Gi, Núñez, Gabriel, Gupta, Dipika, Dziarski, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671207/
https://ncbi.nlm.nih.gov/pubmed/19218085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.12.010
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