Cloning, purification and preliminary crystallographic analysis of cobalamin methyltransferases from Rhodobacter capsulatus

Of the 30 biosynthetic steps necessary for the production of cobalamin (vitamin B(12)), eight involve the addition of S-adenosylmethionine-derived methyl groups to the tetrapyrrole framework. These eight methyl additions are catalysed by six canonical methyltransferase domains and one noncanonical m...

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Bibliographic Details
Main Authors: Seyedarabi, Arefeh, Hutchison, Thomas, To, Teng Teng, Deery, Evelyne, Brindley, Amanda, Warren, Martin J., Pickersgill, Richard W.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2010
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998376/
https://ncbi.nlm.nih.gov/pubmed/21139217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110042910
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