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Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition

Medial prefrontal cortex (mPFC) is known to be involved in relapse after cocaine withdrawal, but the underlying cellular mechanism remains largely unknown. Here we report that after terminating repeated cocaine exposure in rats, a gradual increase in the expression of brain-derived neurotrophic fact...

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Detalhes bibliográficos
Main Authors: Lu, Hui, Cheng, Pei-lin, Lim, Byung Kook, Khoshnevisrad, Nina, Poo, Mu-ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998346/
https://ncbi.nlm.nih.gov/pubmed/20826313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.08.012
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