Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition

Medial prefrontal cortex (mPFC) is known to be involved in relapse after cocaine withdrawal, but the underlying cellular mechanism remains largely unknown. Here we report that after terminating repeated cocaine exposure in rats, a gradual increase in the expression of brain-derived neurotrophic fact...

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Hlavní autoři: Lu, Hui, Cheng, Pei-lin, Lim, Byung Kook, Khoshnevisrad, Nina, Poo, Mu-ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998346/
https://ncbi.nlm.nih.gov/pubmed/20826313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.08.012
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