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Mutual Antagonism Between the Anaphase Promoting Complex and the Spindle Assembly Checkpoint Contributes to Mitotic Timing in Caenorhabditis elegans

The anaphase promoting complex/cyclosome (APC/C) triggers the separation of sister chromatids and exit from mitosis across eukaryotic evolution. The APC/C is inhibited by the spindle assembly checkpoint (SAC) until all chromosomes have achieved bipolar attachment, but whether the APC/C reciprocally...

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Autors principals: Bezler, Alexandra, Gönczy, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998310/
https://ncbi.nlm.nih.gov/pubmed/20944014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.123133
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