CatSper1 required for evoked Ca(2+) entry and control of flagellar function in sperm

CatSper family proteins are putative ion channels expressed exclusively in membranes of the sperm flagellum and required for male fertility. Here, we show that mouse CatSper1 is essential for depolarization-evoked Ca(2+) entry and for hyperactivated movement, a key flagellar function. CatSper1 is no...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Carlson, Anne E., Westenbroek, Ruth E., Quill, Timothy, Ren, Dejian, Clapham, David E., Hille, Bertil, Garbers, David L., Babcock, Donner F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC299831/
https://ncbi.nlm.nih.gov/pubmed/14657352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536658100
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