CatSper1 required for evoked Ca(2+) entry and control of flagellar function in sperm

CatSper family proteins are putative ion channels expressed exclusively in membranes of the sperm flagellum and required for male fertility. Here, we show that mouse CatSper1 is essential for depolarization-evoked Ca(2+) entry and for hyperactivated movement, a key flagellar function. CatSper1 is no...

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Detalhes bibliográficos
Main Authors: Carlson, Anne E., Westenbroek, Ruth E., Quill, Timothy, Ren, Dejian, Clapham, David E., Hille, Bertil, Garbers, David L., Babcock, Donner F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299831/
https://ncbi.nlm.nih.gov/pubmed/14657352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536658100
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