CatSper1 required for evoked Ca(2+) entry and control of flagellar function in sperm

CatSper family proteins are putative ion channels expressed exclusively in membranes of the sperm flagellum and required for male fertility. Here, we show that mouse CatSper1 is essential for depolarization-evoked Ca(2+) entry and for hyperactivated movement, a key flagellar function. CatSper1 is no...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Carlson, Anne E., Westenbroek, Ruth E., Quill, Timothy, Ren, Dejian, Clapham, David E., Hille, Bertil, Garbers, David L., Babcock, Donner F.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2536658100
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