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Incubated protein reduction and digestion on an EWOD digital microfluidic chip for MALDI-MS

Localized heating of droplets on an electrowetting-on-dielectric (EWOD) chip has been implemented and shown to accelerate trypsin digestion reaction rates, sample drying, and matrix crystallization for matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS). Achieving this involved...

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Detalhes bibliográficos
Main Authors: Nelson, Wyatt C., Peng, Ivory, Lee, Geun-An, Loo, Joseph A., Garrell, Robin L., Kim, Chang-Jin “CJ”
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998283/
https://ncbi.nlm.nih.gov/pubmed/21058643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac101833b
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