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Incubated protein reduction and digestion on an EWOD digital microfluidic chip for MALDI-MS
Localized heating of droplets on an electrowetting-on-dielectric (EWOD) chip has been implemented and shown to accelerate trypsin digestion reaction rates, sample drying, and matrix crystallization for matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS). Achieving this involved...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998283/ https://ncbi.nlm.nih.gov/pubmed/21058643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac101833b |
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