Mitochondrial NADH Kinase, Pos5p, Is Required for Efficient Iron-Sulfur Cluster Biogenesis in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the mitochondrial inner membrane readily allows transport of cytosolic NAD(+), but not NADPH, to the matrix. Pos5p is the only known NADH kinase in the mitochondrial matrix. The enzyme phosphorylates NADH to NADPH and is the major source of NADPH in the matrix. The impor...

Full description

Saved in:
Bibliographic Details
Main Authors: Pain, Jayashree, Balamurali, M. M., Dancis, Andrew, Pain, Debkumar
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998133/
https://ncbi.nlm.nih.gov/pubmed/20889970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.178947
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items