MicroRNA (miRNA)-mediated Interaction between Leukemia/Lymphoma-related Factor (LRF) and Alternative Splicing Factor/Splicing Factor 2 (ASF/SF2) Affects Mouse Embryonic Fibroblast Senescence and Apoptosis

Leukemia/lymphoma-related factor (LRF) is a transcriptional repressor, which by recruiting histone deacetylases specifically represses p19/ARF expression, thus behaving as an oncogene. Conversely, in mouse embryonic fibroblasts (MEF), LRF inhibition causes aberrant p19ARF up-regulation resulting in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Verduci, Lorena, Simili, Marcella, Rizzo, Milena, Mercatanti, Alberto, Evangelista, Monica, Mariani, Laura, Rainaldi, Giuseppe, Pitto, Letizia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998123/
https://ncbi.nlm.nih.gov/pubmed/20923760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114736
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados