Genomics-driven Reconstruction of Acinetobacter NAD Metabolism: INSIGHTS FOR ANTIBACTERIAL TARGET SELECTION

Enzymes involved in the last steps of NAD biogenesis, nicotinate mononucleotide adenylyltransferase (NadD) and NAD synthetase (NadE), are conserved and essential in most bacterial species and are established targets for antibacterial drug development. Our genomics-based reconstruction of NAD metabol...

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Hlavní autoři: Sorci, Leonardo, Blaby, Ian, De Ingeniis, Jessica, Gerdes, Svetlana, Raffaelli, Nadia, de Crécy Lagard, Valérie, Osterman, Andrei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998121/
https://ncbi.nlm.nih.gov/pubmed/20926389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185629
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