Genomics-driven Reconstruction of Acinetobacter NAD Metabolism: INSIGHTS FOR ANTIBACTERIAL TARGET SELECTION

Enzymes involved in the last steps of NAD biogenesis, nicotinate mononucleotide adenylyltransferase (NadD) and NAD synthetase (NadE), are conserved and essential in most bacterial species and are established targets for antibacterial drug development. Our genomics-based reconstruction of NAD metabol...

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Detalhes bibliográficos
Main Authors: Sorci, Leonardo, Blaby, Ian, De Ingeniis, Jessica, Gerdes, Svetlana, Raffaelli, Nadia, de Crécy Lagard, Valérie, Osterman, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998121/
https://ncbi.nlm.nih.gov/pubmed/20926389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.185629
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