Effects of Actin-Myosin Kinetics on the Calcium Sensitivity of Regulated Thin Filaments

Activation of thin filaments in striated muscle occurs when tropomyosin exposes myosin binding sites on actin either through calcium-troponin (Ca-Tn) binding or by actin-myosin (A-M) strong binding. However, the extent to which these binding events contributes to thin filament activation remains unc...

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Main Authors: Sich, Nicholas M., O'Donnell, Timothy J., Coulter, Sarah A., John, Olivia A., Carter, Michael S., Cremo, Christine R., Baker, Josh E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Molecular Biophysics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998111/
https://ncbi.nlm.nih.gov/pubmed/20889979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142232
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