Angiotensin-converting Enzyme Overexpression in Mouse Myelomonocytic Cells Augments Resistance to Listeria and Methicillin-resistant Staphylococcus aureus

Gene targeting in ES cells was used to substitute control of angiotensin converting enzyme (ACE) expression from the endogenous promoter to the mouse c-fms promoter. The result is an animal model called ACE 10/10 in which ACE is overexpressed by monocytes, macrophages, and other myelomonocytic linea...

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Autores principales: Okwan-Duodu, Derick, Datta, Vivekanand, Shen, Xiao Z., Goodridge, Helen S., Bernstein, Ellen A., Fuchs, Sebastien, Liu, George Y., Bernstein, Kenneth E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998083/
https://ncbi.nlm.nih.gov/pubmed/20937811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.163782
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