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Synthesis of (2R, 3R)-epigallocatechin-3-O-(4-hydroxybenzoate), a novel catechin from Cistus salvifolius, and evaluation of its proteasome inhibitory activities

The total and semi syntheses of (2R, 3R)-epigallocatechin-3-O-(4-hydroxybenzoate), a novel catechin from Cistus salvifolius, was accomplished. The proteasome inhibition and cytotoxic activities of the synthetic compound and its acetyl derivative were studied and compared with (2R, 3R)-epigallocatech...

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Detalhes bibliográficos
Main Authors: Osanai, Kumi, Huo, Congde, Landis-Piwowar, Kristin R., Dou, Q. Ping, Chan, Tak Hang
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998073/
https://ncbi.nlm.nih.gov/pubmed/21152270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.05.043
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