A stress-responsive system for mitochondrial protein degradation

We show that Ydr049 (renamed VCP/ Cdc48-associated Mitochondrial Stress-responsive—Vms1), a member of an unstudied pan-eukaryotic protein family, translocates from the cytosol to mitochondria upon mitochondrial stress. Cells lacking Vms1 show progressive mitochondrial failure, hypersensitivity to ox...

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Hoofdauteurs: Heo, Jin-Mi, Livnat-Levanon, Nurit, Taylor, Eric B., Jones, Kevin T., Dephoure, Noah, Ring, Julia, Xie, Jianxin, Brodsky, Jeffrey L., Madeo, Frank, Gygi, Steven P., Ashrafi, Kaveh, Glickman, Michael H., Rutter, Jared
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998070/
https://ncbi.nlm.nih.gov/pubmed/21070972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.10.021
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