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Polymorphisms in TBX21 and STAT4 Increase the Risk of Systemic Sclerosis: Evidence of Possible Gene–Gene Interaction and Alterations in Th1/Th2 Cytokines
OBJECTIVE: Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and internal organs. Dysregulation of the immune system, including the Th1/Th2 cytokine balance, is central to the pathogenesis of SSc. This study was undertaken to investigate the hypothesis that sing...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998060/ https://ncbi.nlm.nih.gov/pubmed/19950257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24958 |
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