Nalaganje...
Internalization of p53(14–29) peptide amphiphiles and subsequent endosomal disruption results in SJSA-1 cell death
In vivo peptide inhibition of tumor suppressor p53 binding to the protein MDM2 is hampered by inefficient delivery of the peptide. Our approach to couple a hydrophobic lipid-like tail on the inhibitory peptide p53(14–29) allowed its intracellular delivery in vitro, in a panel of different cell lines...
Shranjeno v:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997927/ https://ncbi.nlm.nih.gov/pubmed/20822110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100193h |
| Oznake: |
Označite
Brez oznak, prvi označite!
|