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Small molecule regulators of Rb-E2F pathway as modulators of transcription
The retinoblastoma tumor suppressor protein, Rb, plays a major role in the regulation of mammalian cell cycle progression. It has been shown that Rb function is essential for the proper modulation of G1/S transition and inactivation of Rb contributes to deregulated cell proliferation. Rb exerts its...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997897/ https://ncbi.nlm.nih.gov/pubmed/20637913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2010.07.004 |
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