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Regulation of VEGF receptors by Rb and E2F1: Role of acetylation

E2F transcription factors regulate a variety of cellular processes but their role in angiogenesis is not clear. We find that many genes involved in angiogenesis like FLT-1, KDR and angiopoietin 2 have potential E2F1 binding sites in their promoter. ChIP assays showed that E2F1 can associate with the...

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Bibliografiske detaljer
Main Authors: Pillai, Smitha, Kovacs, Michelle, Chellappan, Srikumar
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891185/
https://ncbi.nlm.nih.gov/pubmed/20516113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0501
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