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PTEN inhibitors cause a negative inotropic and chronotropic effect in mice
Inactivation of phosphatase and tensin homologue deleted on chromosome ten (PTEN) decreases cardiac contractility under basal conditions and induces cardioprotection against ischemia-reperfusion injury. However, the pharmacological effect of PTEN inhibitors on cardiac contractility has not been stud...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997895/ https://ncbi.nlm.nih.gov/pubmed/20951693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.09.069 |
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