Redox regulation of surface protein thiols: Identification of integrin α-4 as a molecular target by using redox proteomics

Thiols affect a variety of cell functions, an effect known as redox regulation. We show here that treatment (1–2 h) of cells with 0.1–5 mM N-acetyl-l-cysteine (NAC) increases surface protein thiol expression in human peripheral blood mononuclear cells. This effect is not associated with changes in c...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Laragione, Teresa, Bonetto, Valentina, Casoni, Filippo, Massignan, Tania, Bianchi, Giancarlo, Gianazza, Elisabetta, Ghezzi, Pietro
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299788/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657342/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2434516100
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