Catalysis and rotation of F(1) motor: Cleavage of ATP at the catalytic site occurs in 1 ms before 40° substep rotation

F(1), a water-soluble portion of F(o)F(1)-ATP synthase, is an ATP hydrolysis-driven rotary motor. The central γ-subunit rotates in the α(3)β(3) cylinder by repeating the following four stages of rotation: ATP-binding dwell, rapid 80° substep rotation, interim dwell, and rapid 40° substep rotation. A...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Shimabukuro, Katsuya, Yasuda, Ryohei, Muneyuki, Eiro, Hara, Kiyotaka Y., Kinosita, Kazuhiko, Yoshida, Masasuke
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299784/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657340/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2434983100
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