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Acyl-CoA Binding Protein Gene Ablation Induces Pre-implantation Embryonic Lethality in Mice
Unique among the intracellular lipid binding proteins, acyl-CoA binding protein (ACBP) exclusively binds long-chain fatty acyl-CoAs (LCFA-CoAs). To test if ACBP is an essential protein in mammals, the ACBP gene was ablated by homologous recombination in mice. While ACBP heterozygotes appeared phenot...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2997683/ https://ncbi.nlm.nih.gov/pubmed/20559753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11745-010-3437-9 |
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