Deletion of CD14 Attenuates Alzheimer's Disease Pathology by Influencing the Brain's Inflammatory Milieu

Alzheimer's disease (AD) is characterized by the deposition of β-amyloid (Aβ)-containing plaques within the brain that is accompanied by a robust microglial-mediated inflammatory response. This inflammatory response is reliant upon engagement of innate immune signaling pathways involving the to...

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Autors principals: Reed-Geaghan, Erin G., Reed, Quillan W., Cramer, Paige E., Landreth, Gary E.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997622/
https://ncbi.nlm.nih.gov/pubmed/21084593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2637-10.2010
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